It all began in 1764 with the birth of the Funck brewery, later to become the Funck-Bricher brewery, in the Grund in Luxembourg City. Mathias and Isabelle Lentz, the current directors of Brasserie Nationale and Munhowen, came from this brewing family.

Far from the breweries of the capital, Jean-Baptiste Bofferding created the Bofferding brewery in Bascharage in the south of Luxembourg, on the same site where Brasserie Nationale still stands today.

Charles Battin, a spirits merchant, founded his own brewery, Brasserie Battin, in Esch/Alzette in 1937.

Brasserie Nationale was born in 1975 from the merger of Brasserie Funck-Bricher and Brasserie Bofferding. The new company, owned equally by the Bofferding and Lentz families, decided to bring all its production facilities together at the Bascharage site and to produce under a single brand name: Bofferding.

In 1986, Brasserie Nationale launched a series of modernisation projects to enable production on a larger scale.

In a bid to reorganise the distribution of its products, in 1999 Brasserie Nationale acquired Munhowen Distribution, which became the sole retailer of the brewery's products.

The Battin brewery, with which Brasserie Nationale has enjoyed a cordial and commercial relationship for decades, was acquired in 2004. Its production moved to the Bascharage site, while continuing to be produced under the Battin name.

More than 30 years after its disappearance, the Funck-Bricher brand makes a comeback in 2018 with a new low-gluten, organic and vegan beer.

In 2020, Brasserie Nationale announces the launch of its natural mineral water Lodyss. A water of exceptional quality and purity, it has long been used to brew the brewery's beers.